Do you think he can come back from such a situation and realize his dreams again?
Yes, he can come back from the situation but it will not be quick and it will certainly not be easy. What matters most is that recovery is possible even from a place that feels completely broken. your bother is battling a serious gambling addiction and it is a recognized behavioral disorder. Addiction rewires how a person thinks about risk, reward and hope. That is why no matter how smart or disciplined you are, you can still fall prey to it and understanding this and accepting it is important because it will shift the conversation from blame to recovery. This recovery starts the moment he accepts help and commits to change, your concern for him already matters more than you might realize.